
Allergen information
This product is free from all 14 major allergens as defined by UK food supplement labelling regulations — including gluten and soya.
"I went through three rounds of IVF before I really understood CoQ10 — the different forms, the doses being studied and why starting well before treatment mattered. By then, I’d spent countless hours trying to make sense of the research myself.
I created this because I wanted other women to have a straightforward option: naturally fermented ubiquinone, at a meaningful dose, without a long list of unnecessary ingredients."
Why CoQ10 is so interesting in reproductive research
CoQ10 has an established biological role in mitochondrial energy production and antioxidant activity, and has been widely studied in female reproductive research. Here’s the science behind it — and why we chose naturally fermented ubiquinone.
CoQ10 is naturally present in mitochondria, where it plays an essential role in the process used to produce ATP — the cell’s energy currency. Egg cells contain large numbers of mitochondria, and processes including egg maturation are highly energy-dependent. This is one reason CoQ10 and mitochondrial function have become an important area of reproductive research.
CoQ10 acts as an electron carrier within the mitochondrial electron transport chain, transferring electrons between complexes I/II and complex III as part of oxidative phosphorylation and ATP production.
Researchers have investigated whether this biological role may be relevant to reproductive ageing and oocyte function. Laboratory, animal and human fertility research has examined CoQ10 in this context, although research findings should not be interpreted as a guarantee that supplementation will improve egg quality or fertility outcomes.
† No Nutrient Reference Value (NRV) has been established for CoQ10.
CoQ10 has two closely connected biological roles. Alongside its involvement in mitochondrial energy production, its reduced form, ubiquinol, can act as a lipid-soluble antioxidant. The relationship between mitochondrial function, oxidative stress and reproductive ageing is another reason CoQ10 has attracted considerable interest in female fertility research.
CoQ10 cycles between its oxidised form, ubiquinone, and reduced form, ubiquinol. Ubiquinone participates in mitochondrial electron transport, while ubiquinol can act as an antioxidant within lipid membranes.
Oxidative stress and mitochondrial function are both areas of interest in research into reproductive ageing. Clinical studies have therefore investigated CoQ10 supplementation in women undergoing fertility treatment, alongside a wider body of mechanistic and animal research.
† No Nutrient Reference Value (NRV) has been established for CoQ10.
We use naturally fermented ubiquinone in the all-trans form — the same structural configuration found naturally in the body. Ubiquinone is also the form of CoQ10 used in several clinical studies investigating supplementation in women undergoing fertility treatment.
CoQ10 can be produced through different manufacturing methods. Fermentation can be used to produce all-trans ubiquinone, matching the configuration of naturally occurring CoQ10.
We chose ubiquinone deliberately. This form has been used in human fertility research, including randomised controlled trials investigating CoQ10 supplementation before IVF. Fundamental CoQ10 provides 400mg per capsule and 800mg across the recommended daily serving.
† No Nutrient Reference Value (NRV) has been established for CoQ10.